Thanks for the welcome message and the feedback! I’ve been reading more and experimenting more.
I’m 50% to my goal of ~40MH/s or so. Its proven hard to order so many graphics cards, I have to get a volume account setup for my business - so I have been ordering them in small groups.

I currently have three Windows 10 PCs running. This took some effort to get it all running and stable, but it appears like its running well now.
My current configuration is

Windows 10 64-bit on an Asus 19-card mining expert board.
Running 11 cards 5x1070 2x1060 4x1080 hashing right about 10MH/s

Windows 10 64-bit on an Asus H270 Plus board
Running 8 cards 3x1060 1x1070 4x1080 hashing about 6.7MH/s

Windows 10 64-bit on an old HP board
running 3 cards 3x1070 with some experimental modifications … hashing at 3.3MH/s

Currently this puts me right around 20MH/s which is starting to make a good number of coins per day. I am experimenting with some of the profit switching algorithms and direct mining as well as some custom software/scripts that I am developing for mining as well.

I’m hoping I get “most” of my ROI back in about 4 months … we will see!